Camphene – PatientsCann UK

Camphene

2,2-Dimethyl-3-methylenebicyclo[2.2.1]heptane

pronounced: KAM-feen

Smells like a damp fir forest. May support healthy cholesterol levels.

Monoterpene Boiling point: 159°C
Terpene type
Monoterpene
Boiling point
159°C
Primary aroma
Damp Earth
Key effect
Anti-inflammatory

Aroma profile

How it Smells

The aroma of camphene is described as:

Damp EarthFir NeedlesCamphorForest Floor
Found naturally in: Cypress, rosemary, ginger, nutmeg, valerian, sage

Effects

Linked Effects

Anti-inflammatoryPain reliefAntioxidantCardiovascular

These effects are based on early-stage research in animals and cells. They are not proven in humans. Do not change your treatment based on this information.

About

What is Camphene?

Camphene has a distinctive, damp, earthy aroma with strong fir tree and camphor notes. If you have ever walked through a coniferous forest after rain and noticed that sharp, resinous, almost medicinal smell, camphene is a significant part of it. It is also the compound that gives old-fashioned camphor mothballs their smell.

In cannabis, camphene is usually a minor terpene but contributes to the overall earthy, woody character of certain strains. It is a bicyclic monoterpene, meaning its carbon ring structure is folded, which gives it a more complex and persistent smell than simpler linear terpenes (Booth and Bohlmann, 2019).

Effects in detail

What the Research Says

Camphene has a surprisingly diverse preclinical evidence base. Nuutinen (2018) reviewed studies suggesting it has antifungal, antioxidant, and anti-inflammatory properties. Perhaps most unusually among terpenes, there is also early evidence from animal studies that camphene may reduce blood triglycerides and LDL cholesterol.

If confirmed in human trials, this cardiovascular effect would make camphene unique among the 12 terpenes profiled here. However, these are very early-stage findings and cannot be interpreted as evidence that cannabis products will improve cardiovascular health.

Everyday sources

Where You Find it in Daily Life

Rosemary contains camphene alongside pinene and other terpenes, contributing to its sharp, medicinal character. Ginger and nutmeg both contain camphene, adding to their warm, slightly medicinal warmth.

Valerian root, widely sold as a sleep supplement, contains camphene as one of several active aromatic compounds. This may partly explain why valerian is associated with relaxation, though its main sedative compounds are different. Cypress essential oil is one of the richest non-cannabis sources.

Research

Key Studies

Nuutinen (2018) reviewed the available evidence and noted camphene's potential as an antilipidaemic agent based on animal studies, alongside its antimicrobial and antioxidant properties. The review flagged this as an area warranting further investigation in human subjects.

LaVigne et al. (2021) found that camphene, alongside other cannabis terpenes, can modulate cannabinoid receptor activity, placing it within the entourage effect framework. Booth and Bohlmann (2019) noted that camphene's presence in a cannabis terpene profile is often associated with strains grown in cooler climates, where its biosynthesis is favoured.

Back to full Terpenes Guide
Important: The information on this page is for education only. It is not medical advice. Terpene research is still in its early stages. Many studies have been done in animals, not yet in people. Always speak to your doctor before changing your treatment. PatientsCann UK does not recommend any specific cannabis product.

References

  1. Booth, J.K. and Bohlmann, J. (2019) 'Terpenes in Cannabis sativa: from plant genome to humans', Plant Science, 284, pp. 67-72. doi: 10.1016/j.plantsci.2019.03.022.
  2. LaVigne, J.E. et al. (2021) 'Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity', Scientific Reports, 11(1), 8232. doi: 10.1038/s41598-021-87740-8.
  3. Nuutinen, T. (2018) 'Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus', European Journal of Medicinal Chemistry, 157, pp. 198-228. doi: 10.1016/j.ejmech.2018.07.076.